Proteintech, 21149-1-AP, UPK2 Polyclonal antibody

Size: 20ul / 150ul The UPK2 (21149-1-AP) by Proteintech is a Polyclonal antibody targeting UPK2 in IHC, ELISA applications with reactivity to human, mouse samples 21149-1-AP targets UPK2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IHC detected in: human bladder tissue, mouse bladder tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Background Information Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-2 (UPK2) is a single-pass type I membrane protein. UPK2 may play an important role in regulating the assembly of the AUM. Specification Tested Reactivity: human, mouse Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag15694 Product name: Recombinant human UPK2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 41-168 aa of BC113900 Sequence: TESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGGMVVITVLLSVAMF Predict reactive species Full Name: uroplakin 2 Calculated Molecular Weight: 184 aa, 19 kDa Observed Molecular Weight: 28 kDa GenBank Accession Number: BC113900 Gene Symbol: UPK2 Gene ID (NCBI): 7379 RRID: AB_10755290 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O00526 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.