Proteintech, 21437-1-AP, FBXL21 Polyclonal antibody

Size: 20ul / 150ul The FBXL21 (21437-1-AP) by Proteintech is a Polyclonal antibody targeting FBXL21 in IHC, IF/ICC, ELISA applications with reactivity to human, mouse samples 21437-1-AP targets FBXL21 in IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IHC detected in: mouse heart tissue, mouse lung tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive IF/ICC detected in: C2C12 cells Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information FBXL21 (F-box and leucine-rich repeat protein 21) is a member of the F-box protein family, which plays a crucial role in regulating protein degradation through the ubiquitin-proteasome system. FBXL21 has been identified as a regulator in skeletal muscle. It mediates the rhythmic degradation of sarcomere proteins such as TCAP (titin cap) and MYOZ1 (Myozenin1) in conjunction with GSK-3β (PMID: 36574402). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag16049 Product name: Recombinant human FBXL21 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 221-434 aa of BC106753 Sequence: GILCVADRCQGLRELALNYYILTDELFLALSSETHVNLEHLRIDVVSENPGQIKFHAVKKHSWDALIKHSPRVNVVMHFFLYEEEFETFFKEETPVTHLYFGRSVSKVVLGRVGLNCPRLIELVVCANDLQPLDNELICIAEHCTNLTALGLSKCEVSCSAFIRFVRLCERRLTQLSVMEEVLIPDEDYSLDEIHTEVSKYLGRVWFPDVMPLW Predict reactive species Full Name: F-box and leucine-rich repeat protein 21 Calculated Molecular Weight: 434 aa, 49 kDa GenBank Accession Number: BC106753 Gene Symbol: FBXL21 Gene ID (NCBI): 26223 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q3KPF8 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.