Proteintech, 21531-1-AP, GUCA1C Polyclonal antibody

Size: 20ul / 150ul The GUCA1C (21531-1-AP) by Proteintech is a Polyclonal antibody targeting GUCA1C in IHC, ELISA applications with reactivity to human, rat samples 21531-1-AP targets GUCA1C in IHC, ELISA applications and shows reactivity with human, rat samples. Tested Applications Positive IHC detected in: rat eye tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Immunohistochemistry (IHC): IHC : 1:400-1:1600 Background Information The guanylate cyclase-activating proteins (GCAPs), Ca2+-binding proteins of the calmodulin gene superfamily, function as regulators of photoreceptor guanylate cyclases (PMID: 15336959). Three different GCAPs (GCAP1, GCAP2, and GCAP3) are identified in vertebrate retina (PMID: 12596930). The cone-specific guanylate cyclase-activating protein 3 (GCAP3) has been shown to regulate the enzymatic activity of membrane-bound guanylate cyclases (GCs) in bovine and teleost fish photoreceptors, to an extent comparable to that of the paralog protein GCAP1 (PMID: 35328663). Specification Tested Reactivity: human, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag16157 Product name: Recombinant human GUCA1C protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-209 aa of BC103993 Sequence: MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFIDFLEFIAAVNLIVQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK Predict reactive species Full Name: guanylate cyclase activator 1C Calculated Molecular Weight: 209 aa, 24 kDa GenBank Accession Number: BC103993 Gene Symbol: GUCA1C Gene ID (NCBI): 9626 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O95843 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.