Proteintech, 21671-1-AP, RHBDL3 Polyclonal antibody

Size: 20ul / 150ul The RHBDL3 (21671-1-AP) by Proteintech is a Polyclonal antibody targeting RHBDL3 in WB, ELISA applications with reactivity to human samples 21671-1-AP targets RHBDL3 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: SH-SY5Y cells, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information RHBDL3 (Rhomboid-related protein 3) is involved in a process known as regulated intramembrane proteolysis (RIP), where proteins are cleaved within the membrane to release functional polypeptides from their membrane anchors. It is expressed in several structures, including the central nervous system, embryo ectoderm, reproductive system, sensory organ, and thymus. RHBDL3 is also a prognostic marker in Glioblastoma multiforme, indicating its potential role in cancer-related pathways. It is expressed in various cell lines, particularly in those related to neuronal function and visual perception, with low cancer specificity. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag16499 Product name: Recombinant human RHBDL3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-160 aa of BC100975 Sequence: MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCC Predict reactive species Full Name: rhomboid, veinlet-like 3 (Drosophila) Calculated Molecular Weight: 404 aa, 45 kDa Observed Molecular Weight: 40 kDa GenBank Accession Number: BC100975 Gene Symbol: RHBDL3 Gene ID (NCBI): 162494 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P58872 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.