Proteintech, 21777-1-AP, TTF1/NKX2-1 Polyclonal antibody

Size: 20ul / 150ul The TTF1/NKX2-1 (21777-1-AP) by Proteintech is a Polyclonal antibody targeting TTF1/NKX2-1 in WB, ELISA applications with reactivity to human, mouse, rat samples 21777-1-AP targets TTF1/NKX2-1 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, mouse brain tissue, mouse lung tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information NKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family. It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD). The antibody is specific to NKX2-1. Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: NK2 homeobox 1 Calculated Molecular Weight: 42 kDa Observed Molecular Weight: 45-50 kDa GenBank Accession Number: NM_003317 Gene Symbol: TTF1 Gene ID (NCBI): 7080 RRID: AB_2878919 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P43699 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.