Proteintech, 21946-1-AP, SNX18 Polyclonal antibody

Size: 20ul / 150ul The SNX18 (21946-1-AP) by Proteintech is a Polyclonal antibody targeting SNX18 in WB, ELISA applications with reactivity to human samples 21946-1-AP targets SNX18 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HL-60 cells, human placenta tissue, L02 cells, MCF-7 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information SNXs (sorting nexins) are a diverse group of cytoplasmic and membrane-associated proteins that are classified by the presence of a phospholipid-binding motif-the PX domain (PMID:12461558). SNXs are involved in endocytosis and protein trafficking. SNX18, together with SNX9 and SNX33, constitutes a separate SNX9 subfamily which is required for mitosis through endocytosis processes (PMID: 22718350, 20427313). SNX18 acts as a positive regulator of autophagy and regulates ATG9A trafficking from recycling endosomes (PMID: 24113029, 29437695). Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag16645 Product name: Recombinant human SNX18 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 55-284 aa of BC060791 Sequence: YVQVIRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQPPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPT Predict reactive species Full Name: sorting nexin 18 Calculated Molecular Weight: 628 aa, 69 kDa Observed Molecular Weight: 67-70 kDa GenBank Accession Number: BC060791 Gene Symbol: SNX18 Gene ID (NCBI): 112574 RRID: AB_11182387 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q96RF0 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.