Proteintech, 24371-1-AP, TRIM61 Polyclonal antibody

Size: 20ul / 150ul The TRIM61 (24371-1-AP) by Proteintech is a Polyclonal antibody targeting TRIM61 in IHC, IF/ICC, ELISA applications with reactivity to human, mouse samples 24371-1-AP targets TRIM61 in IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive IF/ICC detected in: U2OS cells Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information TRIM61 is a member of the tripartite motif (TRIM) protein family. The RING domain in TRIM proteins, including TRIM61, can mediate the conjugation of proteins with ubiquitin, small ubiquitin-like modifier (SUMO), or the ubiquitin-like molecule IFN-stimulated protein of 15 kDa (ISG15), contributing to the biological flexibility of TRIM proteins. The E3 ligase activity of TRIM proteins, such as TRIM61, is essential for their role in post-translational modification, which plays a crucial role in cellular processes often resulting in targeted degradation of conjugated proteins. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag21656 Product name: Recombinant human TRIM61 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 176-209 aa of BC089393 Sequence: MESPSVTRLECSCTISAHFNLRLPGSSDSSASGS Predict reactive species Full Name: tripartite motif-containing 61 Calculated Molecular Weight: 209 aa, 24 kDa GenBank Accession Number: BC089393 Gene Symbol: TRIM61 Gene ID (NCBI): 391712 RRID: AB_3669434 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q5EBN2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.