Product Description
Size: 20ul / 150ul
The SETD6 (24377-1-AP) by Proteintech is a Polyclonal antibody targeting SETD6 in WB, ELISA applications with reactivity to human, mouse samples
24377-1-AP targets SETD6 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: RAW 264.7 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
SETD6 also named as SET domain containing 6 is a 473 amino-acid protein, which localizes in the Nucleus. The molecular weight of SETD6 is 53kDa. SETD6 consists of 1 SET domain and belongs to the class V-like SAM-binding methyltransferase superfamily. SETD6 as a protein-lysine N-methyltransferase that specifically monomethylates at Lysine 310 of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag19485 Product name: Recombinant human SETD6 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 124-473 aa of BC022451 Sequence: PLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANISSEYQSIVLPFMEAHPDLFSLGVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS Predict reactive species
Full Name: SET domain containing 6
Calculated Molecular Weight: 473 aa, 53 kDa
Observed Molecular Weight: 53 kDa
GenBank Accession Number: BC022451
Gene Symbol: SETD6
Gene ID (NCBI): 79918
RRID: AB_2879514
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8TBK2
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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