Proteintech, 24634-1-AP, TMPRSS11D Polyclonal antibody

Size: 20ul / 150ul The TMPRSS11D (24634-1-AP) by Proteintech is a Polyclonal antibody targeting TMPRSS11D in WB, ELISA applications with reactivity to human samples 24634-1-AP targets TMPRSS11D in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A-253 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information TMPRSS11D, also known as human airway trypsin-like protease (HAT), is a type II transmembrane serine protease that plays a crucial role in various biological processes, including viral infections and cancer progression. This protease is expressed in the epithelial cells of the respiratory tract and has been implicated in the activation of several viruses, such as SARS-CoV-2. In addition to its role in viral infections, TMPRSS11D has also been involved in cancer progression. High expression levels of TMPRSS11D have been associated with poor overall survival in non-small cell lung cancer. This suggests that TMPRSS11D may contribute to tumor growth and metastasis, making it a potential biomarker and therapeutic target in oncology. (PMID: 28086212, PMID: 40348740) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag17841 Product name: Recombinant human TMPRSS11D protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 47-352 aa of BC125195 Sequence: SYFYRSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGML Predict reactive species Full Name: transmembrane protease, serine 11D Calculated Molecular Weight: 418 aa, 46 kDa Observed Molecular Weight: 46 kDa GenBank Accession Number: BC125195 Gene Symbol: TMPRSS11D Gene ID (NCBI): 9407 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O60235 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.