Proteintech, 25226-1-AP, TRPA1 Polyclonal antibody

Size: 20ul / 150ul The TRPA1 (25226-1-AP) by Proteintech is a Polyclonal antibody targeting TRPA1 in WB, ELISA applications with reactivity to human samples 25226-1-AP targets TRPA1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A549 cells, U2OS cells Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information TRPA1 (Transient Receptor Potential Ankyrin 1) is a member of the transient receptor potential (TRP) channel family and is a non-selective cation channel. TRPA1 is predominantly expressed in sensory neurons and is involved in a variety of physiological activities, such as stabilizing cellular membrane potentials, maintaining cellular fluid homeostasis, and regulating intercellular signaling. TRPA1 is a multimodal cell membrane receptor that senses different stimuli and upon activation generates action potential signals via osmolality, temperature and inflammatory factors. TRPA1 has been associated with neurogenic inflammation, osteoarthritis, atopic dermatitis, asthma, inflammatory bowel disease, migraine headache, cancer pain, gout and other diseases, and it is a promising target for drug therapy. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag18685 Product name: Recombinant human TRPA1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-350 aa of BC153003 Sequence: MKRSLRKMWRPGEKKEPQGVVYEDVPDDTEDFKESLKVVFEGSAYGLQNFNKQKKLKRCDDMDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILAT Predict reactive species Full Name: transient receptor potential cation channel, subfamily A, member 1 Calculated Molecular Weight: 1119 aa, 128 kDa Observed Molecular Weight: 130 kDa GenBank Accession Number: BC153003 Gene Symbol: TRPA1 Gene ID (NCBI): 8989 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O75762 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.