Proteintech, 25518-1-AP, PGAM2-Specific Polyclonal antibody

Size: 20ul / 150ul The PGAM2-Specific (25518-1-AP) by Proteintech is a Polyclonal antibody targeting PGAM2-Specific in WB, ELISA applications with reactivity to human, mouse samples 25518-1-AP targets PGAM2-Specific in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse testis tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Phosphoglycerate mutase (PGAM), an important enzyme in the glycolytic pathway, catalyzes the transfer of a phosphate group between the 2 and the 3 positions of glyceric acid. The muscle-specific isoform (type M, PGAM2) of phosphoglycerate mutase (PGAM) is a housekeeping enzyme and it catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate in the glycolysis process to release energy. It is encoded by the Pgam2 gene. In addition, it is demonstrated that PGAM2 locates both in cytoplasm and nuclei, and takes part in the glycometabolism process of cytoplasm and nuclei(PMID: 18499067). Defects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10). This antibody is specific for PGAM2. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: phosphoglycerate mutase 2 (muscle) Calculated Molecular Weight: 28 kDa Observed Molecular Weight: 29 kDa GenBank Accession Number: NM_000290 Gene Symbol: PGAM2 Gene ID (NCBI): 5224 RRID: AB_2880115 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P15259 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.