Product Description
Size: 20ul / 150ul
The LRRC52 (25584-1-AP) by Proteintech is a Polyclonal antibody targeting LRRC52 in WB, ELISA applications with reactivity to human, mouse, rat samples
25584-1-AP targets LRRC52 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse skeletal muscle tissue, rat skeletal muscle tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
LRRC52 (leucine-rich repeat-containing protein 52) belongs to the gamma family of the BK channel accessory subunits, which potentially regulate the channel's gating properties (PMID: 22547800). It is dominantly expressed in testis and skeletal muscle, with much lower expression in several other tissues including placenta, kidney, lung, and some glands. LRRC52 has been reported as a Slo3 auxiliary subunit that helps define the specific alkalization dependence of KSper activation. LRRC52 has a calcular molecular weight of 35 kDa. This polyclonal antibody raised against 24-244aa of human LRRC52 reveals a band of 45 kDa, which is consistent with the molecular weight of glycosylated form of LRRC52 (PMID: 22084117).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag22354 Product name: Recombinant human LRRC52 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 24-244 aa of BC132981 Sequence: SKCPNNCLCQAQEVICTGKQLTEYPLDIPLNTRRLFLNENRITSLPAMHLGLLSDLVYLDCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLSLHKFTFANTTSLRYLDLRNTGLQTLDSAALYHLTTLETLFLSGNPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVEPTELTGWPITRVGNPLRYMCITHLDHKD Predict reactive species
Full Name: leucine rich repeat containing 52
Calculated Molecular Weight: 313 aa, 35 kDa
Observed Molecular Weight: 45 kDa
GenBank Accession Number: BC132981
Gene Symbol: LRRC52
Gene ID (NCBI): 440699
RRID: AB_2880140
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8N7C0
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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