Proteintech, 26356-1-AP, DCUN1D3 Polyclonal antibody

Size: 20ul / 150ul The DCUN1D3 (26356-1-AP) by Proteintech is a Polyclonal antibody targeting DCUN1D3 in WB, ELISA applications with reactivity to human samples 26356-1-AP targets DCUN1D3 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: MCF-7 cells, A549 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information DCUN1D3, also named as SCCRO3, is proposed to function as a tumor suppressor. DCUN1D3 antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, DCUN1D3 may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag23730 Product name: Recombinant human DCUN1D3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-304 aa of BC040442 Sequence: MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAEAATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCPEEQT Predict reactive species Full Name: DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) Observed Molecular Weight: 34 kDa GenBank Accession Number: BC040442 Gene Symbol: DCUN1D3 Gene ID (NCBI): 123879 RRID: AB_2880489 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8IWE4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.