Proteintech, 26428-1-AP, RASSF3 Polyclonal antibody

Size: 20ul / 150ul The RASSF3 (26428-1-AP) by Proteintech is a Polyclonal antibody targeting RASSF3 in WB, IF/ICC, ELISA applications with reactivity to human samples 26428-1-AP targets RASSF3 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: LNCaP cells Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800 Background Information RASSF3 (Ras Association Domain Family Member 3) is an emerging tumor suppressor protein and a key member of the RASSF family, characterized by a conserved Ras Association (RA) domain. RASSF3 acts as a critical node in multiple tumor-suppressive pathways. It directly stabilizes and activates the p53 protein, thereby inducing cell cycle arrest and apoptosis. RASSF3 also contributes to the maintenance of genomic integrity by participating in the DNA damage response. Furthermore, it modulates major signaling cascades such as the Hippo and NF-κB pathways, influencing cell proliferation, survival, and inflammation. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag15801 Product name: Recombinant human RASSF3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 14-127 aa of BC100952 Sequence: KVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPE Predict reactive species Full Name: Ras association (RalGDS/AF-6) domain family member 3 Calculated Molecular Weight: 238 aa, 28 kDa Observed Molecular Weight: 28-30 kDa GenBank Accession Number: BC100952 Gene Symbol: RASSF3 Gene ID (NCBI): 283349 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q86WH2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.