Proteintech, 27422-1-AP, PRR11 Polyclonal antibody

Size: 20ul / 150ul The PRR11 (27422-1-AP) by Proteintech is a Polyclonal antibody targeting PRR11 in WB, ELISA applications with reactivity to human samples 27422-1-AP targets PRR11 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A549 cells, HeLa cells, L02 cells, MCF-7 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:5000 Background Information PRR11, or Proline-rich protein 11, is a protein-coding gene situated on chromosome 17q22-23, which plays a significant role in various cellular processes. The protein itself is composed of a nuclear localization signal (NLS), two proline-rich regions (PRs), and a zinc finger domain (ZFD) (PMID: 36551227). PRR11 has been implicated in the regulation of cell cycle, and it is involved in multiple aspects of cancer biology, including proliferation, migration, invasion, cell-cycle progression, apoptosis, autophagy, and chemotherapy resistance. It serves as a prognostic indicator in certain human cancers and is considered a potential target for therapeutic interventions (PMID: 36739300). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag26636 Product name: Recombinant human PRR11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 181-360 aa of BC008669 Sequence: ASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLRKVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN Predict reactive species Full Name: proline rich 11 Calculated Molecular Weight: 360 aa, 40 kDa Observed Molecular Weight: 38 kDa GenBank Accession Number: BC008669 Gene Symbol: PRR11 Gene ID (NCBI): 55771 RRID: AB_3669600 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q96HE9 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.