Proteintech, 27767-1-AP, Jagged1/CD339 Polyclonal antibody

Size: 20ul / 150ul The Jagged1/CD339 (27767-1-AP) by Proteintech is a Polyclonal antibody targeting Jagged1/CD339 in WB, ELISA applications with reactivity to human samples 27767-1-AP targets Jagged1/CD339 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HUVEC cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag26633 Product name: Recombinant human Jagged1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1094-1218 aa of BC098393 Sequence: RKRRKPGSHTHSASEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKARFAKQPAYTLVDREEKPPNGTLTKHPNWTNKQDNRDLESAQSLNRMEYIV Predict reactive species Full Name: jagged 1 (Alagille syndrome) Calculated Molecular Weight: 1218 aa, 134 kDa Observed Molecular Weight: 150-180 kDa GenBank Accession Number: BC098393 Gene Symbol: Jagged1 Gene ID (NCBI): 182 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P78504 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.