Proteintech, 27921-1-AP, PI3 Kinase p110 Alpha Polyclonal antibody

Size: 20ul / 150ul The PI3 Kinase p110 Alpha (27921-1-AP) by Proteintech is a Polyclonal antibody targeting PI3 Kinase p110 Alpha in WB, ELISA applications with reactivity to Human, mouse, rat samples 27921-1-AP targets PI3 Kinase p110 Alpha in WB, CoIP, ELISA applications and shows reactivity with Human, mouse, rat samples. Tested Applications Positive WB detected in: Jurkat cells, mouse brain tissue, NIH/3T3 cells, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB). Specification Tested Reactivity: Human, mouse, rat Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag27539 Product name: Recombinant human PIK3CA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 345-550 aa of BC113601 Sequence: NVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDF Predict reactive species Full Name: phosphoinositide-3-kinase, catalytic, alpha polypeptide Calculated Molecular Weight: 1068 aa, 124 kDa Observed Molecular Weight: 110 kDa GenBank Accession Number: BC113601 Gene Symbol: PIK3CA Gene ID (NCBI): 5290 RRID: AB_2918135 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P42336 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.