Proteintech, 28893-1-AP, Phospho-SMAD1 (Ser206) Polyclonal antibody

Size: 20ul / 100ul The Phospho-SMAD1 (Ser206) (28893-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-SMAD1 (Ser206) in WB, ELISA applications with reactivity to Human samples 28893-1-AP targets Phospho-SMAD1 (Ser206) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: BMP2 treated HepG2 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Transforming growth factor-β (TGF-β) superfamily is recognized as one of the largest families of secreted multifunctional peptides exerting different biological effects on a large variety of cell types, such as regulation of hormone secretion, stimulation of extracellular matrix formation, the inhibition of proliferation of many cell types, cell survival, bone formation, and chemotaxis for inflammatory cells. One of the most important proteins that modulate TGF-β ligand activity is the SMAD family proteins. SMAD1 is one of the receptor-activated Smads. It's also a signal transducers of BMP signaling and binds to several proteins involved in ubiquitin-proteasome system (UPS). Specification Tested Reactivity: Human Cited Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: SMAD family member 1 Calculated Molecular Weight: 52 kDa Observed Molecular Weight: 60 kDa GenBank Accession Number: BC001878 Gene Symbol: SMAD1 Gene ID (NCBI): 4086 RRID: AB_2881229 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q15797 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.