Proteintech, 28907-1-AP, Phospho-JUN (Ser63) Polyclonal antibody

Size: 20ul / 100ul The Phospho-JUN (Ser63) (28907-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-JUN (Ser63) in WB, ELISA applications with reactivity to human, mouse samples 28907-1-AP targets Phospho-JUN (Ser63) in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: Anisomycin treated NIH/3T3 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information JUN, the most extensively studied protein of the activator protein-1 (AP-1) complex, is involved in numerous cell activities, such as proliferation, apoptosis, survival, tumorigenesis and tissue morphogenesis (PMID: 22180088). JUN is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. JUN is a basic leucine zipper (bZIP) transcription factor that acts as homo- or heterodimer, binding to DNA and regulating gene transcription (PMID: 9732876). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: jun oncogene Calculated Molecular Weight: 331 aa, 36 kDa Observed Molecular Weight: 40-45 kDa GenBank Accession Number: BC068522 Gene Symbol: JUN Gene ID (NCBI): 3725 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P05412 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.