Proteintech, 28951-1-AP, Phospho-STAT5A (Ser726)/STAT5B (Ser731) Polyclonal antibody

Size: 20ul / 100ul The Phospho-STAT5A (Ser726)/STAT5B (Ser731) (28951-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-STAT5A (Ser726)/STAT5B (Ser731) in WB, ELISA applications with reactivity to human samples 28951-1-AP targets Phospho-STAT5A (Ser726)/STAT5B (Ser731) in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: GM-CSF treated TF-1 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information STAT5A, also named as STAT5, belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different GHs. This antibody can recognize the phosphorylation of STAT5A at Ser726 and the phosphorylation of STAT5B at Ser731. Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: signal transducer and activator of transcription 5A Calculated Molecular Weight: 794 aa, 92 kDa Observed Molecular Weight: 90-95 kDa GenBank Accession Number: BC027036 Gene Symbol: STAT5A Gene ID (NCBI): 6776 RRID: AB_2918220 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P42229 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, and 0.05% BSA, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.