Proteintech, 29034-1-AP, Phospho-TBC1D1 (Ser660) Polyclonal antibody

Size: 20ul / 100ul The Phospho-TBC1D1 (Ser660) (29034-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-TBC1D1 (Ser660) in WB, ELISA applications with reactivity to Human samples 29034-1-AP targets Phospho-TBC1D1 (Ser660) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: Calyculin A treated HeLa cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information TBC1D1 belong to the family of RabGAPs and its physiological roles in glucose homeostasis and its implication in human diseases have already been characterized in skeletal muscle and adipocytes in a large number of independent studies. TBC1D1 including twophospho-tyrosine-binding (PTB) domains, a calmodulin-binding domain(CBD) and the func-tional GAP domain responsible for catalyzing GTP hydrolysis. TBC1D1 is phosphorylated by AMPK at Ser660 and Thr237, and by AKT at Thr596. The RabGAPs TBC1D1 is important regulators of glucose homeostasis inskeletal muscle and adipose tissue. (PMID: 31627187, PMID: 18477703) Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 Calculated Molecular Weight: 133 kDa Observed Molecular Weight: 160 kDa GenBank Accession Number: BC050321 Gene Symbol: TBC1D1 Gene ID (NCBI): 23216 RRID: AB_2918232 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q86TI0 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, and 0.05% BSA, pH 7.3. Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage.