Product Description
Size: 20ul / 150ul
The LPHN1 (30142-1-AP) by Proteintech is a Polyclonal antibody targeting LPHN1 in IHC, IF-P, ELISA applications with reactivity to human, mouse, rat samples
30142-1-AP targets LPHN1 in IHC, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive IHC detected in: mouse brain tissue, rat kidney tissue, mouse kidney tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF-P detected in: mouse kidney tissue
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:50-1:500
Immunofluorescence (IF)-P: IF-P : 1:50-1:500
Background Information
Latrophilin-1 (LPHN1) was isolated as the main high-affinity receptor for α-latrotoxin from black widow spider venom, a powerful presynaptic secretagogue (PMID: 30967757). aGPCR latrophilin 1 (ADGRL1/LPHN1) is involved in controlling energy balance and food intake. Although this receptor is present in adipocytes and many neurons, where it is essential for axon growth cone formation and neuronal. It is present in Adipocytes and many neurons, where it is essential for Axon growth cone formation and neuronal function (PMID: 38664368).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag31093 Product name: Recombinant human LPHN1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 400-500 aa of NM_001008701 Sequence: DPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVE Predict reactive species
Full Name: latrophilin 1
Calculated Molecular Weight: 163 kDa
GenBank Accession Number: NM_001008701
Gene Symbol: LPHN1
Gene ID (NCBI): 22859
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: O94910
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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