Proteintech, 30455-1-AP, NLRC3 Polyclonal antibody

Size: 20ul / 150ul The NLRC3 (30455-1-AP) by Proteintech is a Polyclonal antibody targeting NLRC3 in WB, ELISA applications with reactivity to Human samples 30455-1-AP targets NLRC3 in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: Daudi cells, Jurkat cells, Raji cells, Ramos cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells. Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag32323 Product name: Recombinant human NLRC3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-130 aa of NM_178844 Sequence: MRKQEVRTGREAGQGHGTGSPAEQVKALMDLLAGKGSQGSQAPQALDRTPDAPLGPCSNDSRIQRHRKALLSKVGGGPELGGPWHRLASLLLVEGLTDLQLREHDFTQVEATRGGGHPARTVALDRLFLP Predict reactive species Full Name: NLR family, CARD domain containing 3 Calculated Molecular Weight: 115 kDa Observed Molecular Weight: 100-110 kDa GenBank Accession Number: NM_178844 Gene Symbol: NLRC3 Gene ID (NCBI): 197358 RRID: AB_3086322 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q7RTR2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.