Proteintech, 30610-1-AP, SIX6OS1 Polyclonal antibody

Size: 20ul / 150ul The SIX6OS1 (30610-1-AP) by Proteintech is a Polyclonal antibody targeting SIX6OS1 in WB, ELISA applications with reactivity to human samples 30610-1-AP targets SIX6OS1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: COLO 320 cells, Jurkat cells, SGC-7901 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information SIX6OS1 (SIX6 Opposite Strand 1) is a nuclear protein that plays a core role in the process of meiosis. It is a key scaffold protein that constitutes the central element of the synaptonemal complex, directly interacting with proteins such as SYCE1 to ensure the proper pairing, synapsis, and genetic recombination of homologous chromosomes. Its function is crucial for the formation of stable chiasmata, which are the basis for genetic diversity and the accurate segregation of chromosomes. Mutations in the SIX6OS1 gene can disrupt this process, leading to errors in chromosome separation and are one of the important genetic factors causing primary ovarian insufficiency in humans and non-obstructive azoospermia in males, directly associated with reproductive disorders. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag33548 Product name: Recombinant human C14orf39 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 200-420 aa of BC125070 Sequence: SNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSIENDSDEVEERAENFPR Predict reactive species Full Name: chromosome 14 open reading frame 39 Calculated Molecular Weight: 587 aa, 68 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC125070 Gene Symbol: C14orf39 Gene ID (NCBI): 317761 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8N1H7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.