Proteintech, 30887-1-AP, Phospho-p130Cas / BCAR1 (Tyr410) Polyclonal antibody

Size: 20ul / 100ul The Phospho-p130Cas / BCAR1 (Tyr410) (30887-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-p130Cas / BCAR1 (Tyr410) in WB, ELISA applications with reactivity to Human samples 30887-1-AP targets Phospho-p130Cas / BCAR1 (Tyr410) in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: pervanadate treated HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information p130Cas, encoded by the breast cancer anti-estrogen resistance 1 (BCAR1) gene, is a scaffold protein that integrates large multi-protein complexes in response to stimuli such as hormones, growth factors, and integrin engagement. Upon environmental signals, Src family members and focal adhesion kinase (FAK) phosphorylate the p130Cas substrate domain (SD). This active p130Cas can recruit adaptor proteins such as Crk and Nck to its phosphorylated SD. (PMID: 34830244) Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: breast cancer anti-estrogen resistance 1 Calculated Molecular Weight: 870 aa, 93 kDa Observed Molecular Weight: 130 kDa GenBank Accession Number: BC062556 Gene Symbol: BCAR1 Gene ID (NCBI): 9564 RRID: AB_3669775 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P56945 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.