Proteintech, 30916-1-AP, SCN4B Polyclonal antibody

Size: 20ul / 150ul The SCN4B (30916-1-AP) by Proteintech is a Polyclonal antibody targeting SCN4B in WB, ELISA applications with reactivity to human samples 30916-1-AP targets SCN4B in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HepG2 cells, SH-SY5Y cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Mammalian sodium channels are heterotrimers, composed of a central, pore-forming alpha subunit and two auxiliary beta subunits (PMID: 11486343). SCN4B (sodium channel subunit beta-4) is one of several sodium channel beta subunits, which modulate channel gating kinetics. SCN4B has an N-terminal signal peptide, a large extracellular domain predicted to form an Ig-like fold, a single transmembrane alpha helix, and a short cytoplasmic C terminus. Defects in the SCN4B gene are a cause of long QT syndrome type 10 (LQT10). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag34123 Product name: Recombinant human SCN4B protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 31-162 aa of NM_174934.3 Sequence: LEVSVGKATDIYAVNGTEILLPCTFSSCFGFEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTV Predict reactive species Full Name: sodium channel, voltage-gated, type IV, beta Calculated Molecular Weight: 25 kDa Observed Molecular Weight: 25 kDa GenBank Accession Number: NM_174934.3 Gene Symbol: SCN4B Gene ID (NCBI): 6330 RRID: AB_3669784 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q8IWT1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.