Proteintech, 31108-1-AP, CBX1 Polyclonal antibody

Size: 20ul / 150ul The CBX1 (31108-1-AP) by Proteintech is a Polyclonal antibody targeting CBX1 in WB, ELISA applications with reactivity to human, mouse samples 31108-1-AP targets CBX1 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: A431 cells, MCF-7 cells, HEK-293 cells, NIH/3T3 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information CBX1 (chromobox 1), also known as CBX. It is expected to be located in nucleus, the protein is expressed in all adult and embryonic tissues. It is a member of the heterochromatin protein family. CBX1 is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. It may play an important role in the epigenetic control of chromatin structure and gene expression. The calculated molecular weight of CBX1 is 21 kDa. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag34901 Product name: Recombinant human CBX1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 60-115 aa of BC002609 Sequence: CPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFAR Predict reactive species Full Name: chromobox homolog 1 (HP1 beta homolog Drosophila ) Calculated Molecular Weight: 27 kDa Observed Molecular Weight: 21-27 kDa GenBank Accession Number: BC002609 Gene Symbol: CBX1 Gene ID (NCBI): 10951 RRID: AB_3669859 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: P83916 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.