Proteintech, 31577-1-AP, SCRT1 Polyclonal antibody

Size: 20ul / 150ul The SCRT1 (31577-1-AP) by Proteintech is a Polyclonal antibody targeting SCRT1 in WB, ELISA applications with reactivity to human, mouse samples 31577-1-AP targets SCRT1 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: TT cells, mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information SCRT1 (Transcriptional repressor scratch 1), which is expressed in many tissues, especially in brain and adrenal gland. In addition, SCRT1 is also expressed in islet β cells, and its expression is related to insulin secretion ability. SCRT1 is a C2H2 zinc finger transcription inhibitor, which can bind to E-box motif. The encoded protein may promote nerve differentiation and may be related to cancer with neuroendocrine characteristics. The functions of SCRT1 in islet β cells include regulating the expression and secretion of insulin and influencing the proliferation of β cells. SCRT1 may control calcineurin /NFAT signaling pathway by affecting the expression of Syt4, Notch1, Nfatc1 and Nfatc2 genes, which is an important regulator of the growth and function of β cells (PMID: 33309639). The molecular weight of SCRT1 is 36 kDa. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag36215 Product name: Recombinant human SCRT1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-195 aa of BC168377 Sequence: MPRSFLVKKVKLDAFSSADLESAYGRARSDLGAPLHDKGYLSDYVGPSSVYDGDAEAALLKGPSPEPMYAAAVRGELGPAAAGSAPPPTPRPELATAAGGYINGDAAVSEGYAADAFFITDGRSRRKASNAGAAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGE Predict reactive species Full Name: scratch homolog 1, zinc finger protein (Drosophila) Observed Molecular Weight: 36 kDa GenBank Accession Number: BC168377 Gene Symbol: SCRT1 Gene ID (NCBI): 83482 RRID: AB_3670042 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q9BWW7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.