Proteintech, 31705-1-AP, IKBKAP Polyclonal antibody

Size: 20ul / 150ul The IKBKAP (31705-1-AP) by Proteintech is a Polyclonal antibody targeting IKBKAP in WB, ELISA applications with reactivity to Human samples 31705-1-AP targets IKBKAP in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: HeLa cells, HepG2 cells, U-251 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:12000 Background Information IKBKAP, also known as ELP1. It is expected to be located in the cytoplasm and nucleus, which is ubiquitinated in adrenal and ovary tissue. The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. And it exists in homodimer. The molecular weight of IKBKAP is 150 kDa. Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag35286 Product name: Recombinant human IKBKAP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1131-1332 aa of NM_001318360.1 Sequence: FSRHKKRLLVVRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD Predict reactive species Full Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Calculated Molecular Weight: 150kDa，1332aa Observed Molecular Weight: 140-150 kDa GenBank Accession Number: NM_001318360.1 Gene Symbol: IKBKAP Gene ID (NCBI): 8518 RRID: AB_3670089 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: O95163 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.