Proteintech, 31841-1-AP, FAAP100 Polyclonal antibody

Size: 20ul / 150ul The FAAP100 (31841-1-AP) by Proteintech is a Polyclonal antibody targeting FAAP100 in WB, ELISA applications with reactivity to human samples 31841-1-AP targets FAAP100 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A431 cells, HL-60 cells, Jurkat cells, SH-SY5Y cells Recommended dilution Western Blot (WB): WB : 1:500-1:3000 Background Information FA core complex associated protein 100 (FAAP100, also known as C17orf70) is a component of the Fanconi anemia (FA), which plays a role in the FA-associated DNA damage response network as well as regulates Fanconi anemia group D2 protein (FANCD2) monoubiquitination and the stability of the FA core complex (PMID: 17396147). FAAP100 deletion leads to FA pathway inactivation, increases TRCs and cotranscriptional R-loops, and contributes to the collapse of replication forks and the generation of DNA damage (PMID: 37580696). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag36385 Product name: Recombinant human C17orf70 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 524-730 aa of BC117139 Sequence: PVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQAAQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL Predict reactive species Full Name: chromosome 17 open reading frame 70 Calculated Molecular Weight: 93 kDa Observed Molecular Weight: 100 kDa GenBank Accession Number: BC117139 Gene Symbol: C17orf70 Gene ID (NCBI): 80233 RRID: AB_3670125 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q0VG06 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.