Proteintech, 31892-1-AP, MTERF4 Polyclonal antibody

Size: 20ul / 150ul The MTERF4 (31892-1-AP) by Proteintech is a Polyclonal antibody targeting MTERF4 in WB, ELISA applications with reactivity to human samples 31892-1-AP targets MTERF4 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HT-1080 cells, HeLa cells, HepG2 cells, LNCaP cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information The MTERF protein family plays a key role in controlling mitochondrial DNA gene expression in mammals. Mitochondrial transcription termination factor 4 (MTERF4, also known as MTERFD2) regulates mitochondrial ribosome biogenesis and translation (PMID: 21531335). It can form a stoichiometric complex with the ribosomal RNA methyl-transferase NSUN4 and is necessary for the recruitment of this factor to the large ribosomal subunit. Loss of MTERF4 leads to defective ribosomal assembly and a drastic reduction in translation (PMID: 21531335). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag32334 Product name: Recombinant human MTERFD2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 43-381 aa of NM_182501 Sequence: LTTASNGGVIEELSCVRSNNYVQEPECRRNLVQCLLEKQGTPVVQGSLELERVMSSLLDMGFSNAHINELLSVRRGASLQQLLDIISEFILLGLNPEPVCVVLKKSPQLLKLPIMQMRKRSSYLQKLGLGEGKLKRVLYCCPEIFTMRQQDINDTVRLLKEKCLFTVQQVTKILHSCPSVLREDLGQLEYKFQYAYFRMGIKHPDIVKSEYLQYSLTKIKQRHIYLERLGRYQTPDKKGQTQIPNPLLKDILRVSEAEFLARTACTSVEEFQVFKKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE* Predict reactive species Full Name: MTERF domain containing 2 Calculated Molecular Weight: 44 kDa Observed Molecular Weight: 37 kDa GenBank Accession Number: NM_182501 Gene Symbol: MTERFD2 Gene ID (NCBI): 130916 RRID: AB_3670135 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: Q7Z6M4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.