Product Description
Size: 20ul / 150ul
The TNRC18 (32165-1-AP) by Proteintech is a Polyclonal antibody targeting TNRC18 in WB, ELISA applications with reactivity to human, mouse samples
32165-1-AP targets TNRC18 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: BxPC-3 cells, HepG2 cells, MDA-MB-453 cells, mouse kidney tissue, mouse testis tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:3000
Background Information
Trinucleotide repeat containing 18 (TNRC18, also known as CAGL79 and KIAA1856) is a nucleic-acid-binding protein, which recognizes H3K9me3 to mediate the silencing of ERV class I (ERV1) elements and acts as a chromatin-associated regulator of ERVs (PMID: 27980689; 37938770). It is located in the cytosol, mitochondrion, and nucleus (PMID: 19262598). The mutation in TNRC18 may cause Fazio-Londe disease (PMID: 38188848).
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag37483 Product name: Recombinant human TNRC18 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1238-1400 aa of BC131808 Sequence: PCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELER Predict reactive species
Full Name: trinucleotide repeat containing 18
Calculated Molecular Weight: 31 kDa
Observed Molecular Weight: 29 kDa
GenBank Accession Number: BC131808
Gene Symbol: TNRC18
Gene ID (NCBI): 84629
RRID: AB_3670212
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: O15417
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924