Proteintech, 32803-1-AP, Serpinc1 Polyclonal antibody

Size: 20ul / 150ul The Serpinc1 (32803-1-AP) by Proteintech is a Polyclonal antibody targeting Serpinc1 in WB, ELISA applications with reactivity to human, mouse, rat samples 32803-1-AP targets Serpinc1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: human serum, mouse liver tissue, rat liver tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information SERPINC1 is a gene encoding antithrombin, also known as antithrombin III. The main function of antithrombin is to inhibit coagulation proteases such as thrombin and factor Xa, thereby preventing excessive coagulation and maintaining normal hemostasis and blood flow. Mutations in the SERPINC1 gene can lead to antithrombin deficiency (ATD), which is an autosomal dominant genetic disorder. The expression profile/molecular weight observed is consistent with what has been described in the literature (PMID: 3609301, PMID: 25485983, PMID: 35935621). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Eg2949 Product name: recombinant mouse Serpinc1 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 33-465 aa of NM_080844.4 Sequence: HGNPVDDICIAKPRDIPVNPLCIYRSPGKKATEEDGSEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVSDAFHKAFLEVNEEGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGRVANPCVN Predict reactive species Full Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Calculated Molecular Weight: 52 kDa Observed Molecular Weight: 55 kDa GenBank Accession Number: NM_080844.4 Gene Symbol: Serpinc1 Gene ID (NCBI): 11905 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity Purification UNIPROT ID: P32261 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.