Product Description
Size: 20ul / 150ul
The CFAP221 (32922-1-AP) by Proteintech is a Polyclonal antibody targeting CFAP221 in WB, ELISA applications with reactivity to human samples
32922-1-AP targets CFAP221 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: MG-63 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
CFAP221 (also known as PCDP1) is a crucial structural protein in motile cilia and sperm flagella. It is specifically located within the axillary shaft of the cilia and acts as a "connection bridge" between the adjacent outer doublet microtubules, playing a role in stabilizing the core skeleton of the axillary shaft and coordinating the sliding of microtubules. The loss of this protein's function will disrupt the structural integrity and normal oscillation of the cilia, leading to a genetic disorder known as primary ciliary dyskinesia.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag38512 Product name: Recombinant human hCG_17324 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 265-508 aa of NM_001271049.1 Sequence: LEEFERLNTLSKKVNVPPEKAMMHINFHRPPAKPKPQKVKEIEYQNLRFPVDLSNPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDIHEEMENHLKWQVHLGKDPMSFKLKKELTEEWQKACAKYKLDRGDPILDEEFQRLKTEVSHKRVVRNQEEKIKEFHPTFDPLINNTWLSRSRAQKRFQQVARKVMIQGRLFNMLSAVREMDKESILRKIGQAKQSIAQEAN Predict reactive species
Full Name: primary ciliary dyskinesia protein 1
Calculated Molecular Weight: 97kDa,840a
Observed Molecular Weight: 100 kDa
GenBank Accession Number: NM_001271049.1
Gene Symbol: hCG_17324
Gene ID (NCBI): 200373
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q4G0U5
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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