Product Description
Size: 20ul / 150ul
The C4orf32 (33453-1-AP) by Proteintech is a Polyclonal antibody targeting C4orf32 in WB, ELISA applications with reactivity to human samples
33453-1-AP targets C4orf32 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: human placenta tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
The FAM241A protein, also known as C4orf32, is a key regulatory factor that is localized to the Golgi apparatus. It plays an important role in maintaining the structural integrity of the Golgi apparatus and is involved in processes such as protein glycosylation and vesicle transport. More importantly, FAM241A has been identified as a novel negative regulator of the Hippo signaling pathway. It directly binds to and inhibits the activity of the core kinases MST1/2, thereby relieving the suppression of the downstream effectors YAP/TAZ, promoting cell proliferation, and inhibiting apoptosis. Aberrant function of FAM241A is closely related to the occurrence and development of various human diseases, especially tumors, making it a highly promising target for basic research and clinical translation.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag38764 Product name: Recombinant human C4orf32 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-99 aa of BC022534 Sequence: MCSAGELLRGGDGGERDEDGDALAEREAAGTEWDPGASQRRRGQRQKESEQDVEDSQNHTGEPVGDDYKKMGTLFGELNKNLINMGFTRMYFGERIVEP Predict reactive species
Full Name: chromosome 4 open reading frame 32
Observed Molecular Weight: 20 kDa
GenBank Accession Number: BC022534
Gene Symbol: C4orf32
Gene ID (NCBI): 132720
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity Purification
UNIPROT ID: Q8N8J7
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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