Product Description
Size: 20ul / 150ul
The p38 MAPK (51115-1-AP) by Proteintech is a Polyclonal antibody targeting p38 MAPK in WB, ELISA applications with reactivity to human, mouse, rat samples
51115-1-AP targets p38 MAPK in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse ovary tissue, NIH/3T3 cells, PC-12 cells, RAW 264.7 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing. This antibody is specific to MAPK14.
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, mouse, rat, pig
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: Peptide Predict reactive species
Full Name: mitogen-activated protein kinase 14
Calculated Molecular Weight: 360 aa, 41 kDa
Observed Molecular Weight: 38 kDa
GenBank Accession Number: BC031574
Gene Symbol: p38 MAPK
Gene ID (NCBI): 1432
RRID: AB_3086430
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q16539
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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