Proteintech, 55105-1-AP, MAGEA1 Polyclonal antibody

Size: 20ul / 150ul The MAGEA1 (55105-1-AP) by Proteintech is a Polyclonal antibody targeting MAGEA1 in WB, IF/ICC, ELISA applications with reactivity to human samples 55105-1-AP targets MAGEA1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A375 cells, MCF-7 cells Positive IF/ICC detected in: A375 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Immunofluorescence (IF)/ICC: IF/ICC : 1:20-1:200 Background Information MAGEA1, also named as CT1.1, MZ2-E, MAGE1 and MAGE1A, is the first gene reported to encode a CTL-defined human tumor antigen. It may play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 provided direct evidence for the power of the cDNA expression library as an effective strategy to identify genes encoding tumor antigens recognized by HLA-restricted T cells.(PMID:16951217 ) The antibody is specific to MAGEA1. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: melanoma antigen family A, 1 (directs expression of antigen MZ2-E) Calculated Molecular Weight: 34 kDa Observed Molecular Weight: 46 kDa GenBank Accession Number: NM_004988 Gene Symbol: MAGEA1 Gene ID (NCBI): 4100 RRID: AB_10859942 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P43355 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.