Proteintech, 55360-1-AP, CHRNE Polyclonal antibody

Size: 20ul / 150ul The CHRNE (55360-1-AP) by Proteintech is a Polyclonal antibody targeting CHRNE in WB, ELISA applications with reactivity to human, mouse, rat samples 55360-1-AP targets CHRNE in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse heart tissue, rat heart tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Acetylcholine receptor subunit epsilon is a protein that in humans is encoded by the CHRNE gene. Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: cholinergic receptor, nicotinic, epsilon Calculated Molecular Weight: 55 kDa Observed Molecular Weight: 40-50 kDa GenBank Accession Number: NM_000080 Gene Symbol: CHRNE Gene ID (NCBI): 1145 RRID: AB_3086443 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q04844 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.