Product Description
Size: 20ul / 150ul
The NR1H3 (60134-1-Ig) by Proteintech is a Monoclonal antibody targeting NR1H3 in WB, ELISA applications with reactivity to human, rat, pig samples
60134-1-Ig targets NR1H3 in WB, IHC, IF, ELISA applications and shows reactivity with human, rat, pig samples.
Tested Applications
Positive WB detected in: T-47D cells, HepG2 cells, MCF-7 cells, COLO 320 cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Background Information
NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.
Specification
Tested Reactivity: human, rat, pig
Cited Reactivity: human, mouse
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag6184 Product name: Recombinant human NR1H3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 104-402 aa of BC041172 Sequence: KCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE Predict reactive species
Full Name: nuclear receptor subfamily 1, group H, member 3
Calculated Molecular Weight: 50 kDa
Observed Molecular Weight: 44 kDa
GenBank Accession Number: BC041172
Gene Symbol: NR1H3
Gene ID (NCBI): 10062
RRID: AB_2154887
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: Q13133
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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