Proteintech, 60153-1-Ig, ABCD1 Monoclonal antibody

Size: 20ul / 150ul The ABCD1 (60153-1-Ig) by Proteintech is a Monoclonal antibody targeting ABCD1 in WB, IF/ICC, ELISA applications with reactivity to human samples 60153-1-Ig targets ABCD1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HeLa cells Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag12757 Product name: Recombinant human ABCD1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 358-745 aa of BC025358 Sequence: SESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST Predict reactive species Full Name: ATP-binding cassette, sub-family D (ALD), member 1 Calculated Molecular Weight: 745 aa, 83 kDa Observed Molecular Weight: 75 kDa GenBank Accession Number: BC025358 Gene Symbol: ABCD1 Gene ID (NCBI): 215 RRID: AB_10640436 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P33897 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.