Product Description
Size: 20ul / 150ul
The KCNN4 (60276-1-Ig) by Proteintech is a Monoclonal antibody targeting KCNN4 in WB, ELISA applications with reactivity to human, mouse, rat samples
60276-1-Ig targets KCNN4 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: human blood tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, mouse, rat
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag19774 Product name: Recombinant human KCNN4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 128-427 aa of BC015337 Sequence: VQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK Predict reactive species
Full Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Calculated Molecular Weight: 427 aa, 48 kDa
Observed Molecular Weight: 48 kDa
GenBank Accession Number: BC015337
Gene Symbol: KCNN4
Gene ID (NCBI): 3783
RRID: AB_2881395
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: O15554
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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