Proteintech, 60345-1-Ig, NR1H2 Monoclonal antibody

Size: 20ul / 150ul The NR1H2 (60345-1-Ig) by Proteintech is a Monoclonal antibody targeting NR1H2 in WB, ELISA applications with reactivity to human, pig samples 60345-1-Ig targets NR1H2 in WB, ELISA applications and shows reactivity with human, pig samples. Tested Applications Positive WB detected in: human liver tissue, pig liver tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information NR1H2, also known as LXRB, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It preferentially bind to double-stranded oligonucleotide direct repeats, which have the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). It involves in the regulation of cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Specification Tested Reactivity: human, pig Cited Reactivity: human, mouse Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag5635 Product name: Recombinant human NR1H2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-461 aa of BC047750 Sequence: MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE Predict reactive species Full Name: nuclear receptor subfamily 1, group H, member 2 Calculated Molecular Weight: 51 kDa Observed Molecular Weight: 51 kDa GenBank Accession Number: BC047750 Gene Symbol: NR1H2 Gene ID (NCBI): 7376 RRID: AB_2881454 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: P55055 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.