Proteintech, 65047-1-Ig, Anti-Mouse CD103 (2E7)

Size: 100ug / 500ug The CD103 (65047-1-Ig) by Proteintech is a Monoclonal antibody targeting CD103 in FC applications with reactivity to mouse samples 65047-1-Ig targets CD103 in IHC, IF, FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension Background Information CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890). Specification Tested Reactivity: mouse Cited Reactivity: mouse Host / Isotype: Armenian Hamster / IgG Class: Monoclonal Type: Antibody Immunogen: C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) Predict reactive species Full Name: integrin alpha E, epithelial-associated GenBank Accession Number: BC150690 Gene Symbol: CD103 Gene ID (NCBI): 16407 RRID: AB_2918359 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: Q60677 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.