Proteintech, 65075-1-Ig, Anti-Human ICAM-1/CD54 (15.2)

Size: 100ug / 500ug The ICAM-1/CD54 (65075-1-Ig) by Proteintech is a Monoclonal antibody targeting ICAM-1/CD54 in FC applications with reactivity to human samples 65075-1-Ig targets ICAM-1/CD54 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension Background Information ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784). Specification Tested Reactivity: human Host / Isotype: Mouse / IgG1, kappa Class: Monoclonal Type: Antibody Immunogen: Rheumatoid synovial cells and human monocytes Predict reactive species Full Name: intercellular adhesion molecule 1 Calculated Molecular Weight: 90 kDa GenBank Accession Number: BC015969 Gene Symbol: ICAM-1 Gene ID (NCBI): 3383 ENSEMBL Gene ID: ENSG00000090339 RRID: AB_2918379 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P05362 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.