Proteintech, 65093-1-Ig, Anti-Mouse IL-7Ra/CD127 (A7R34)

Size: 500ug The IL-7Ra/CD127 (65093-1-Ig) by Proteintech is a Monoclonal antibody targeting IL-7Ra/CD127 in FC applications with reactivity to mouse samples 65093-1-Ig targets IL-7Ra/CD127 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension Background Information CD127, also known as IL-7R subunit alpha (IL-7Rα), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells (PMID: 8415665). IL-7R is a heterodimer composed of CD127 and IL-2Rγ (CD132), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15 (PMID: 8266077; 9862091). IL-7R plays critical roles in lymphocyte development and homeostasis (PMID: 26336149). CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP) (PMID: 10974032). Specification Tested Reactivity: mouse Host / Isotype: Rat / IgG2a, kappa Class: Monoclonal Type: Antibody Immunogen: IL-7Ra-IgG1 fusion protein Predict reactive species Full Name: interleukin 7 receptor GenBank Accession Number: BC089571 Gene Symbol: CD127 Gene ID (NCBI): 16197 RRID: AB_3670272 Conjugate: Unconjugated Form: Liquid Purification Method: Affinity purification UNIPROT ID: P16872 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.