Proteintech, 65575-1-MR, Anti-Human CD20 (2H7) Mouse IgG2a Recombinant Antibody

Size: 100ug The CD20 (65575-1-MR) by Proteintech is a Recombinant antibody targeting CD20 in FC applications with reactivity to human, monkey, non-human primates samples 65575-1-MR targets CD20 in FC applications and shows reactivity with human, monkey, non-human primates samples. Tested Applications Positive FC detected in: human PBMCs, cynomolgus PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD20 is a 33-37 kDa transmembrane phosphoprotein belonging to the membrane-spanning 4A family (PMID: 3260267; 16785532). CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells (PMID: 7524522). CD20 functions as calcium-permeable cation channel (PMID: 7684739). It is involved in the regulation of B-cell activation, proliferation and differentiation (PMID: 7524522). Specification Tested Reactivity: human, monkey, non-human primates Host / Isotype: Mouse / IgG2a Class: Recombinant Type: Antibody Immunogen: Human tonsillar B cells Predict reactive species Full Name: membrane-spanning 4-domains, subfamily A, member 1 Calculated Molecular Weight: 297 aa, 33 kDa GenBank Accession Number: BC002807 Gene Symbol: CD20 Gene ID (NCBI): 931 RRID: AB_3670329 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P11836-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.