Proteintech, 65670-1-TR, Anti-Mouse CD11a (M17/4) Rat IgG2a Recombinant Antibody

Size: 100ug The CD11a (65670-1-TR) by Proteintech is a Recombinant antibody targeting CD11a in FC applications with reactivity to mouse samples 65670-1-TR targets CD11a in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse thymocytes Recommended dilution Flow Cytometry (FC): FC : 0.5 ug per 10^6 cells in a 100 µl suspension Background Information CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160). Specification Tested Reactivity: mouse Host / Isotype: Rat / IgG2a Class: Recombinant Type: Antibody Immunogen: N/A Predict reactive species Full Name: integrin alpha L GenBank Accession Number: BC145802 Gene Symbol: CD11a Gene ID (NCBI): 16408 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: B7ZN92 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.