Proteintech, 66145-1-Ig, IL-16 Monoclonal antibody

Size: 20ul / 150ul The IL-16 (66145-1-Ig) by Proteintech is a Monoclonal antibody targeting IL-16 in WB, ELISA applications with reactivity to human samples 66145-1-Ig targets IL-16 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Recombinant protein Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Specification Tested Reactivity: human Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag16466 Product name: Recombinant human IL-16 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 154-454 aa of BC040272 Sequence: MTKKSAAPTDRQPYSLCSNRKSLSQQLDCPAGKAAGTSRPTRSLSTAQLVQPSGGLQASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRLTAPPSLCSHLSPPLCRSLSSSTCITKDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVSIIVSRHPDPQKEEMEAQEVK Predict reactive species Full Name: interleukin 16 (lymphocyte chemoattractant factor) Calculated Molecular Weight: 130 aa, 15 kDa Observed Molecular Weight: 37 kDa GenBank Accession Number: BC040272 Gene Symbol: IL-16 Gene ID (NCBI): 3603 RRID: AB_2881542 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q14005 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.