Proteintech, 66228-1-Ig, RND3 Monoclonal antibody

Size: 20ul / 150ul The RND3 (66228-1-Ig) by Proteintech is a Monoclonal antibody targeting RND3 in WB, ELISA applications with reactivity to human, pig samples 66228-1-Ig targets RND3 in WB, IF, ELISA applications and shows reactivity with human, pig samples. Tested Applications Positive WB detected in: fetal human brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation. Specification Tested Reactivity: human, pig Cited Reactivity: human Host / Isotype: Mouse / IgG2b Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag18839 Product name: Recombinant human RND3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-244 aa of BC012513 Sequence: MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM Predict reactive species Full Name: Rho family GTPase 3 Calculated Molecular Weight: 244 aa, 27 kDa Observed Molecular Weight: 29 kDa GenBank Accession Number: BC012513 Gene Symbol: RND3 Gene ID (NCBI): 390 RRID: AB_2881619 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P61587 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.