Proteintech, 66371-1-Ig, GDF10 Monoclonal antibody

Size: 20ul / 150ul The GDF10 (66371-1-Ig) by Proteintech is a Monoclonal antibody targeting GDF10 in WB, ELISA applications with reactivity to human, pig, rat samples 66371-1-Ig targets GDF10 in WB, ELISA applications and shows reactivity with human, pig, rat samples. Tested Applications Positive WB detected in: pig bone marrow tissue, ROS1728 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Growth differentiation factor-10 (GDF10), also known as BMP3b, is a member of the transforming growth factor-b (TGF-b) superfamily. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. GDF10 plays a role in head formation and may have multiple roles in skeletal morphogenesis. Additionally, GDF10 may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. Specification Tested Reactivity: human, pig, rat Cited Reactivity: rat Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag4906 Product name: Recombinant human GDF10 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-288 aa of BC028237 Sequence: MALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAAQATGPLQDNELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR Predict reactive species Full Name: growth differentiation factor 10 Calculated Molecular Weight: 53 kDa Observed Molecular Weight: 53 kDa GenBank Accession Number: BC028237 Gene Symbol: GDF10 Gene ID (NCBI): 2662 RRID: AB_2881750 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P55107 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.